New findings on intercellular communication in the tumour environment

A recent publication in the FASEB journal (Burtey et al., 2015), arising from the collaboration of the NorLux Neuro-Oncology Laboratory (Department of Oncology) and the University of Bergen, was highlighted in a press release edited by FASEB: “Cancer cells use secret tunnels to communicate and smuggle cancer signals to their neighbours.”

In the study, the authors examined the intercellular transfer of organelles and proteins in vitro and in vivo and the role of so-called tunnelling nanotubes, membrane bridges that facilitate the transfer process. The NorLux co-workers significantly contributed to the in vivo experiments using mouse xenografts.

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A proteomics approach to assess the response to drug treatment in brain tumours

Glioblastoma is a highly aggressive brain tumour against which existing treatments are largely inefficient. Oncologists and proteomics experts from the Department of Oncology at LIH now published a research article in the latest issue of the scientific journal ‘Molecular and Cellular Proteomics’ (impact factor 6.56) with promising findings. By using a targeted proteomics approach, they aimed to better monitor the response of glioblastoma to anti-cancer treatment and identified potential biomarker proteins for responsiveness to treatment.

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Healthcare Research Award 2015 for the NorLux Neuro-Oncology Laboratory

The NorLux Neuro-Oncology Laboratory at LIH was rewarded with the Healthcare Research Award at this year’s Luxembourg Healthcare Summit. The team’s work on malignant brain tumours has been considered as a major contribution to national excellence in health research by the award jury.

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The director of KG Jebsen BTRC speaks at the Department of Biomedicine

August 20th 2015 , Prof. Rolf Bjerkvig,  the Director of KG-Jebsen BTRC, held a BBB seminar  at the Department of Biomedicine, University of Bergen, entitled “Malignant brain tumours: Their initiation and progression, -and resistence mechanisms to anti-angiogenic therapy”.

Prof Rolf Bjerkvig awarded by the King of Norway

Prof Rolf Bjerkvig is the head of LIH’s Department of Oncology and at the same time leading the K.G. Jebsen Centre for Brain Tumor Research at the Department of Biomedicine at the University of Bergen in Norway. On 8th  June he was awarded the King Olav V Cancer Research Prize 2015 by His Majesty King Harald V of Norway on behalf of the Norwegian Cancer Society. This prestigious award is a recognition for his exceptional achievements in brain cancer research.

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Norlux group meeting at Bekkjarvik 2015

On June 3rd 2015 Norlux organized a group meeting to update all members on current status of all projects, share new ideas and establish future directions for our collaborations. The meeting was very successful and further strengthened our nice collaboration. The meeting program can be viewed here.

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Successful EACR conference in Luxembourg: Bringing together the international oncology research community

The conference ‘Precision Medicine for Cancer’ , which is part of a new conference series of the European Association for Cancer Research  (EACR), was held from 1st  to 4th  March 2015 within the nice settings of the Neumünster Abbey in the old town of Luxembourg city. Prof Dr Simone Niclou from the NorLux Neuro-Oncology Laboratory was part of the scientific organising committee. Gathering top level scientists together with 116 participants from the field of oncology, young researchers to a large majority, the conference was highly appreciated by all attendees. As much as 95% rated it as ‘very good’ or ‘excellent’ and 99% would recommend it to their peers.

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The Cancer Foundation supports a research project of the NorLux Neuro-Oncology Laboratory

The Cancer Foundation (Fondation Cancer) funds a research project of the NorLux Neuro-Oncology Laboratory entitled ‘targeting glioma cell invasion’ which aims at unravelling the mechanisms underlying cancer cell invasion in glioblastoma (glioma, malignant brain tumours) and at proposing new therapeutic strategies to block tumour progression.

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Two Successful PhD defenses in the NorLux Neuro-Oncology Laboratory

Middle of December, two PhD candidates from the NorLux Neuro-Oncology Laboratory successfully completed their doctoral theses.

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Prof. Dr. Simone Niclou awarded for the best scientific presentation at the EANO meeting

Prof. Dr. Simone Niclou, Head of the NorLux Neuro-Oncology Laboratory of CRP-Santé and Associate Professor at the K.G. Jebsen Brain Tumour Research Centre of the University of Bergen, received a prize for the best scientific presentation held at the 11th  meeting of the European Association for Neuro-Oncology (EANO)  in October 2014 in Turin, Italy.

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